{"id":26788,"date":"2020-10-27T08:30:00","date_gmt":"2020-10-26T23:30:00","guid":{"rendered":"https:\/\/www.heartlife.or.jp\/hospital\/?page_id=26788"},"modified":"2020-10-27T18:08:43","modified_gmt":"2020-10-27T09:08:43","slug":"spade-study","status":"publish","type":"page","link":"https:\/\/www.heartlife.or.jp\/hospital\/department\/pediatrics\/pediatrics-allergy\/spade-study\/","title":{"rendered":"\u725b\u4e73\u30a2\u30ec\u30eb\u30ae\u30fc\u767a\u75c7\u4e88\u9632\u3068\u30b9\u30da\u30fc\u30c9\u8a66\u9a13\u306b\u3064\u3044\u3066"},"content":{"rendered":"\n<p><\/p>\n\n\n\n<div class=\"wp-block-vk-blocks-staff vk_staff vk_staff-layout-imageLeft\"><div class=\"vk_staff_text\"><h3 class=\"vk_staff_text_name\" style=\"color:#0693e3\">\u5d0e\u539f\u5fb9\u88d5<\/h3><p class=\"vk_staff_text_caption\" style=\"color:inherit\">\u3055\u304d\u306f\u3089\u3000\u3066\u3064\u3072\u308d<\/p><p class=\"vk_staff_text_role\" style=\"color:inherit\">\u5c0f\u5150\u79d1\u90e8\u9577<\/p><h4 class=\"vk_staff_text_profileTitle\" style=\"color:#0693e3\">\u89e3\u8aac\u8005\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb<\/h4><p class=\"vk_staff_text_profileText\" style=\"color:inherit\">\u65e5\u672c\u5c0f\u5150\u79d1\u5b66\u4f1a\u5c02\u9580\u533b\u3001\u65e5\u672c\u5c0f\u5150\u79d1\u5b66\u4f1a\u6307\u5c0e\u533b\u3001\u65e5\u672c\u30a2\u30ec\u30eb\u30ae\u30fc\u5b66\u4f1a\u5c02\u9580\u533b<br>\u8fd1\u5e74\u3001\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u304a\u5b50\u3055\u3093\u304c\u5897\u3048\u3066\u3044\u307e\u3059\u3002\u30cd\u30c3\u30c8\u4e0a\u3067\u306f\u6839\u62e0\u306e\u306a\u3044\u60c5\u5831\u304c\u63b2\u8f09\u3055\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002\u6b63\u3057\u3044\u60c5\u5831\u3092\u5171\u6709\u3057\u3001\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u3092\u9632\u3050\u30fb\u6cbb\u3059\u30fb\u5b89\u5168\u306b\u7ba1\u7406\u3059\u308b\u3053\u3068\u3092\u76ee\u6a19\u306b\u4e00\u7dd2\u306b\u9811\u5f35\u3063\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<\/p><\/div><div class=\"vk_staff_photo vk_staff_photo-border-default\"><img decoding=\"async\" class=\"vk_staff_photo_image\" src=\"https:\/\/www.heartlife.or.jp\/hospital\/wp-content\/uploads\/sites\/2\/2020\/10\/Dr_Sakihara-1.jpg\" alt=\"Profile Picture\"\/><\/div><\/div>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright size-large\"><img decoding=\"async\" src=\"https:\/\/www.heartlife.or.jp\/hospital\/wp-content\/uploads\/sites\/2\/2020\/01\/233212-150x150-1.jpg\" alt=\"\" class=\"wp-image-8751\"\/><\/figure><\/div>\n\n\n\n<p>\u3000\u904e\u53bb20\u5e74\u9593\u306b\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u60a3\u8005\u6570\u306f\u5897\u52a0\u3057\u3066\u304a\u308a\u3001\u7279\u306b\u5148\u9032\u56fd\u3067\u306f\u5c0f\u5150\u306e\u7d0410%\u306b\u9054\u3059\u308b\u3068\u3044\u3046\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002<sup>1<\/sup><\/p>\n\n\n\n<p>\u3000\u7c73\u56fd\u5c0f\u5150\u79d1\u5b66\u4f1a\uff08American Academy of Pediatrics\uff0c\u901a\u79f0AAP\uff09\u306f\u30012000\u5e74\u306e\u6642\u70b9\u3067\u306f\u300c\u5bb6\u65cf\u306b\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u3042\u308b\u4e73\u5150\u3067\u306f\u88dc\u5b8c\u98df\uff08\u96e2\u4e73\u98df\uff09\u3092\u751f\u5f8c6\u304b\u6708\u307e\u3067\u306f\u958b\u59cb\u305b\u305a\u3001\u4e73\u88fd\u54c1\u306f1\u6b73\u307e\u3067\u3001\u9d8f\u5375\u306f2\u6b73\u307e\u3067\u3001\u30d4\u30fc\u30ca\u30c3\u30c4\u30fb\u30ca\u30c3\u30c4\u985e\u30fb\u9b5a\u306a\u3069\u306f3\u6b73\u307e\u3067\u4e0e\u3048\u308b\u3079\u304d\u3067\u306f\u306a\u3044\u300d\u3068\u306e\u58f0\u660e\u3092\u767a\u8868\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u305d\u306e\u5f8c\u306e\u591a\u304f\u306e\u89b3\u5bdf\u7814\u7a76\u304b\u3089\u3001\u98df\u3079\u59cb\u3081\u308b\u3053\u3068\u3092\u9045\u3089\u305b\u308b\u3068\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u304c\u5897\u52a0\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u30012008\u5e74\u306b\u306f\u300c\u88dc\u5b8c\u98df\u306e\u958b\u59cb\u3092\u9045\u3089\u305b\u3066\u3082\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u3092\u4e88\u9632\u3059\u308b\u6839\u62e0\u306f\u306a\u3044\u300d\u3068\u65b9\u91dd\u3092\u8ee2\u63db\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.heartlife.or.jp\/hospital\/wp-content\/uploads\/sites\/2\/2020\/01\/233237-150x150-1.jpg\" alt=\"\" class=\"wp-image-8752\"\/><\/figure><\/div>\n\n\n\n<p>\u3000\u305d\u306e\u5f8c\u30012010\u5e74\u4ee3\u306b\u5165\u308a\u89b3\u5bdf\u7814\u7a76\u3060\u3051\u3067\u306a\u304f\u3044\u304f\u3064\u304b\u306e\u4ecb\u5165\u7814\u7a76\u3082\u5831\u544a\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u30022015\u5e74\u306b\u3001\u30a4\u30ae\u30ea\u30b9\u304b\u3089\u30ea\u30fc\u30d7\u8a66\u9a13\uff08LEAP study\uff09\u304c\u5831\u544a\u3055\u308c\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u30ea\u30b9\u30af\u306e\u3042\u308b\u5150\u3067\u306f\u3001\u751f\u5f8c5\uff5e10\u304b\u6708\u524d\u5f8c\u3067\u30d4\u30fc\u30ca\u30c3\u30c4\u86cb\u767d\u306e\u6442\u53d6\u3092\u958b\u59cb\u3059\u308b\u3068\u30d4\u30fc\u30ca\u30c3\u30c4\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u4e88\u9632\u306b\u6709\u52b9\u3067\u3042\u308b\u3053\u3068<sup>2<\/sup>\u304c\u793a\u3055\u308c\u3001\u305d\u306e\u7fcc\u5e74\u306b\u306f\u672c\u90a6\u304b\u3089\u30d7\u30c1\u8a66\u9a13\uff08PETIT study\uff09\u304c\u5831\u544a\u3055\u308c\u3001\u6e7f\u75b9\u306e\u3042\u308b\u5150\u3067\u306f\u6e7f\u75b9\u306e\u6cbb\u7642\u3092\u884c\u3044\u3064\u3064\u751f\u5f8c6\u304b\u6708\u304b\u3089\u5fae\u91cf\u306e\u52a0\u71b1\u5375\u306e\u6442\u53d6\u3092\u958b\u59cb\u3059\u308b\u3068\u9d8f\u5375\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u4e88\u9632\u306b\u6709\u52b9\u3067\u3042\u308b\u3053\u3068<sup>3<\/sup>\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<span data-color=\"#fcb900\" style=\"background: linear-gradient(transparent 60%,rgba(252, 185, 0, 0.7) 0);\" class=\"vk_highlighter\">\u3053\u308c\u3089\u306e\u7814\u7a76\u7d50\u679c\u306e\u89e3\u91c8\u3068\u5fdc\u7528\u306b\u306f\u7559\u610f\u70b9\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u308c\u3067\u3082\u300c<span style=\"color:#0693e3\" class=\"tadv-color\">\u4e73\u5150\u671f\u306e\u65e9\u3044\u6642\u671f\u304b\u3089\u6442\u53d6\u3092\u958b\u59cb\u3059\u308b\u3053\u3068\u3067\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u4e88\u9632\u306b\u52b9\u679c\u304c\u3042\u308a\u305d\u3046\u3067\u3042\u308b<\/span><\/span>\u300d\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u304d\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000\u3057\u304b\u3057\u3001\u30d4\u30fc\u30ca\u30c3\u30c4\u3001\u9d8f\u5375\u3068\u4e26\u3093\u3067\u6709\u75c5\u7387\u306e\u9ad8\u3044\u725b\u4e73\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u4e88\u9632\u306b\u3064\u3044\u3066\u306f\u3001\u3053\u308c\u307e\u3067\u300c\u751f\u5f8c14\u65e5\uff5e3\u304b\u6708\u4ee5\u5185\u306b\u725b\u4e73\u86cb\u767d\uff08\u7c89\u30df\u30eb\u30af\uff09\u3092\u958b\u59cb\u3059\u308b\u3068\u725b\u4e73\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u304c\u5c11\u306a\u3044\u300d\u3068\u3044\u3046\u7d50\u679c\u3092\u793a\u3057\u305f\u89b3\u5bdf\u7814\u7a76\u306f\u3044\u304f\u3064\u304b\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059<sup>4,5,6<\/sup>\u304c\u3001\u4ecb\u5165\u7814\u7a76\u3067\u305d\u306e\u4e88\u9632\u52b9\u679c\u3092\u8a3c\u660e\u3057\u305f\u5831\u544a\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f<sup>7,8,9<\/sup>\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"vk-htags-b302bb80-bdfa-4f38-8758-dcd6b431b591\">\u6c96\u7e04\u770c\u5185\u306e\uff14\u75c5\u9662\u3067SPADE study\uff08\u30b9\u30da\u30fc\u30c9\u8a66\u9a13\uff09\u3092\u5b9f\u65bd<\/h3>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.heartlife.or.jp\/hospital\/wp-content\/uploads\/sites\/2\/2020\/10\/baby_jyunyu_honyubin-e1603696638674.png\" alt=\"\" class=\"wp-image-26959\" width=\"181\" height=\"215\"\/><\/figure><\/div>\n\n\n\n<p>\u3000\u305d\u3053\u3067\u4eca\u56de\u3001<span data-color=\"#fcb900\" style=\"background: linear-gradient(transparent 60%,rgba(252, 185, 0, 0.7) 0);\" class=\"vk_highlighter\">\u4e73\u5150\u671f\u306e\u65e9\u3044\u6642\u671f\u304b\u3089\u306e\u7c89\u30df\u30eb\u30af\u958b\u59cb\u304c\u725b\u4e73\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u4e88\u9632\u306b\u6709\u52b9\u304b\u3069\u3046\u304b\u3092\u691c\u8a0e\u3059\u308b\u305f\u3081\u3001\u6c96\u7e04\u770c\u5185\u306e\uff14\u75c5\u9662\uff08\u30cf\u30fc\u30c8\u30e9\u30a4\u30d5\u75c5\u9662\u3001\u6c96\u7e04\u5354\u540c\u75c5\u9662\u3001\u90a3\u8987\u5e02\u7acb\u75c5\u9662\u3001\u7409\u7403\u5927\u5b66\u75c5\u9662\uff09\u3067\u51fa\u751f\u3057\u305f\u5150\u3092\u5bfe\u8c61\u306b\u30b9\u30da\u30fc\u30c9\u8a66\u9a13\uff08SPADE study\uff09\u3092\u5b9f\u65bd<\/span>\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000\u5bfe\u8c61\u8005\u306f\u3001\u5728\u80ce\u9031\u657035\u9031\u4ee5\u4e0a\u3001\u51fa\u751f\u4f53\u91cd2,000g\u4ee5\u4e0a\u306e\u5150\u3068\u3057\u3001\u3055\u3089\u306b\u91cd\u7be4\u306a\u57fa\u790e\u75be\u60a3\u3084\u5408\u4f75\u75c7\u304c\u3042\u308b\u5834\u5408\u306f\u5bfe\u8c61\u5916\u3068\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000\u53c2\u52a0\u3057\u3066\u304f\u3060\u3055\u3063\u305f\u4e73\u5150\u3092\u3001\u725b\u4e73\u86cb\u767d\uff08\u7c89\u30df\u30eb\u30af\uff09\u3092\u751f\u5f8c1\u304b\u6708\u304b\u30893\u304b\u6708\u306b\u9054\u3059\u308b\u524d\u307e\u3067\uff08\u6b63\u54732\u304b\u6708\u9593\uff091\u65e5\u3042\u305f\u308a10mL\u4ee5\u4e0a\u3092\u6442\u53d6\u3059\u308b\u300c\u6442\u53d6\u7fa4\u300d\u3068\u3001\u7c89\u30df\u30eb\u30af\u306f\u9664\u53bb\u3057\u6bcd\u4e73\u3067\u4e0d\u8db3\u3059\u308b\u5834\u5408\u306f\u5927\u8c46\u7c89\u4e73\u3067\u4ee3\u7528\u3059\u308b\u300c\u9664\u53bb\u7fa4\u300d\u306e\u3044\u305a\u308c\u304b\u306b\u30e9\u30f3\u30c0\u30e0\u306b\u5272\u308a\u5f53\u3066\u3001\u751f\u5f8c6\u304b\u6708\u6642\u70b9\u3067\u306e\u725b\u4e73\u30a2\u30ec\u30eb\u30ae\u30fc\u767a\u75c7\u7387\u3092\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000\u751f\u5f8c5\u65e5\u4ee5\u5185\u306b\u53c2\u52a0\u767b\u9332\u3055\u308c\u305f\u306e\u306f518\u540d\u3067\u3001\u3053\u306e\u3046\u306112\u540d\u306f\u751f\u5f8c1\u304b\u6708\u307e\u3067\u306b\u53c2\u52a0\u3092\u30ad\u30e3\u30f3\u30bb\u30eb\u3055\u308c\u307e\u3057\u305f\u3002\u751f\u5f8c1\u304b\u6708\u6642\u306b\u884c\u3063\u305f\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u691c\u67fb\uff08\u7c89\u30df\u30eb\u30af20mL\u3092\u6442\u53d6\uff09\u3067\u3001\u8541\u9ebb\u75b9\u3092\u8a8d\u3081\u305f\u5150\u304c1\u540d\u3001\u6442\u53d6\u306e\u6570\u6642\u9593\u5f8c\u306b\u5614\u5410\u3092\u8a8d\u3081\u305f\u5150\u304c1\u540d\u3044\u307e\u3057\u305f\u3002\u75c7\u72b6\u3092\u8a8d\u3081\u305f\u5150\u306f\u7814\u7a76\u306e\u7d99\u7d9a\u304c\u5371\u967a\u3068\u5224\u65ad\u3055\u308c\u3001\u901a\u5e38\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u5916\u6765\u3067\u8a3a\u7642\u3092\u7d99\u7d9a\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000\u6b8b\u308b504\u4f8b\u304c\u751f\u5f8c1\u304b\u6708\u6642\u306b\u30e9\u30f3\u30c0\u30e0\u306b\u300c\u6442\u53d6\u7fa4\u300d\u304b\u300c\u9664\u53bb\u7fa4\u300d\u306b\u5272\u308a\u5f53\u3066\u3089\u308c\u3001\u751f\u5f8c3\u304b\u6708\u306b\u9054\u3059\u308b\u307e\u3067\u4ee5\u4e0b\u306e\u30ec\u30b8\u30e1\u30f3\uff08\u30b9\u30da\u30fc\u30c9\u8a66\u9a13\u306e\u8a08\u753b\uff09\u3092\u7d99\u7d9a\u3057\u3066\u3082\u3089\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<ul class=\"is-style-vk-check-circle-mark wp-block-list\"><li><strong><span style=\"color:#0693e3\" class=\"tadv-color\">\u6442\u53d6\u7fa4<\/span>\u2026\u30df\u30eb\u30af\u306e\u6442\u53d6\u306f1\u65e510mL\u4ee5\u4e0a\u3067\u670820\u65e5\u4ee5\u4e0a\u3001\u4e2d\u65ad\u306f1\u9031\u9593\u4ee5\u5185<\/strong><\/li><li><strong><span style=\"color:#cf2e2e\" class=\"tadv-color\">\u9664\u53bb\u7fa4<\/span>\u2026\u30df\u30eb\u30af\u306e\u6442\u53d6\u306f\u670810\u65e5\u672a\u6e80\u3001\u6bcd\u4e73\u3067\u4e0d\u8db3\u3059\u308b\u5834\u5408\u306f\u5927\u8c46\u7c89\u4e73\u3067\u4ee3\u7528<\/strong><\/li><\/ul>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.heartlife.or.jp\/hospital\/wp-content\/uploads\/sites\/2\/2020\/10\/baby_junyu-e1603696773982.png\" alt=\"\" class=\"wp-image-26958\" width=\"159\" height=\"218\"\/><\/figure><\/div>\n\n\n\n<p>\u3000<span data-color=\"#fcb900\" style=\"background: linear-gradient(transparent 60%,rgba(252, 185, 0, 0.7) 0);\" class=\"vk_highlighter\">\u540c\u6642\u306b\u3001\u3069\u3061\u3089\u306e\u7fa4\u306e\u5150\u306b\u5bfe\u3057\u3066\u3082\u53ef\u80fd\u306a\u7bc4\u56f2\u3067\u6bcd\u4e73\u6804\u990a\u3092\u7d99\u7d9a\u3059\u308b\u3088\u3046\u52e7\u3081\u307e\u3057\u305f<\/span>\u3002<\/p>\n\n\n\n<p>\u3000\u751f\u5f8c3\u304b\u6708\u4ee5\u964d\u306f\u3001\u30df\u30eb\u30af\u306e\u5236\u9650\u3084\u6307\u793a\u306f\u884c\u308f\u305a\u81ea\u7531\u306b\u6442\u53d6\u3057\u3066\u3082\u3089\u3044\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u4ecb\u5165\u958b\u59cb\u304b\u3089\u751f\u5f8c6\u304b\u6708\u307e\u3067\u6bce\u6708\u53d7\u8a3a\u3059\u308b\u969b\u306b\u6e7f\u75b9\u306e\u6709\u7121\u3092\u78ba\u8a8d\u3057\u3001\u5fc5\u8981\u306b\u5fdc\u3058\u30b9\u30ad\u30f3\u30b1\u30a2\u6307\u5c0e\u304a\u3088\u3073\u30b9\u30c6\u30ed\u30a4\u30c9\u5916\u7528\u5264\u3084\u4fdd\u6e7f\u5264\u3067\u306e\u6cbb\u7642\u3092\u884c\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000\u5272\u308a\u5f53\u3066\u306e\u7d50\u679c\u3001\u6442\u53d6\u7fa4243\u540d\u3001\u9664\u53bb\u7fa4249\u540d\u306b\u4e0a\u8a18\u306e\u4ecb\u5165\u3092\u884c\u3044\u307e\u3057\u305f\u3002\u4ecb\u5165\u3092\u958b\u59cb\u3059\u308b\u524d\u306e\u60c5\u5831\u3068\u3057\u3066\u3001\u5150\u306e\u5468\u7523\u671f\u6b74\u3084\u5bb6\u65cf\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u6b74\u3001\u30da\u30c3\u30c8\u98fc\u80b2\u6b74\u3001\u65b0\u751f\u5150\u671f\u306e\u30df\u30eb\u30af\u6442\u53d6\u72b6\u6cc1\u306a\u3069\u306f\u4e21\u7fa4\u3067\u5dee\u3092\u8a8d\u3081\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000\u751f\u5f8c6\u304b\u6708\u307e\u3067\u6bce\u6708\u53d7\u8a3a\u3057\u3066\u304f\u3060\u3055\u3063\u305f\u5150\u306f\u3001\u6442\u53d6\u7fa4227\u540d\uff0893.4%\uff09\u9664\u53bb\u7fa4235\u540d\uff0894.3%\uff09\u3067\u3057\u305f\u3002\u4ecb\u5165\u3092\u884c\u3063\u305f\u5150\u306e\u3046\u3061\u3001<span data-color=\"#fcb900\" style=\"background: linear-gradient(transparent 60%,rgba(252, 185, 0, 0.7) 0);\" class=\"vk_highlighter\"><span style=\"color:#0693e3\" class=\"tadv-color\">\u751f\u5f8c6\u304b\u6708\u6642\u306e\u30df\u30eb\u30af100mL\u3092\u6442\u53d6\u3059\u308b\u7d4c\u53e3\u8ca0\u8377\u8a66\u9a13\u3067\u725b\u4e73\u30a2\u30ec\u30eb\u30ae\u30fc\u3068\u8a3a\u65ad\u3055\u308c\u305f\u5272\u5408\u306f\u3001\u6442\u53d6\u7fa42\u4f8b\uff080.8%\uff09\u3001\u9664\u53bb\u7fa417\u4f8b\uff086.8%\uff09\u3068\u306a\u308a\u3001\u6442\u53d6\u7fa4\u3067\u306f\u6709\u610f\u306b\u725b\u4e73\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u304c\u5c11\u306a\u3044\u3068\u3044\u3046\u7d50\u679c<\/span><\/span>\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1020\" height=\"620\" src=\"https:\/\/www.heartlife.or.jp\/hospital\/wp-content\/uploads\/sites\/2\/2020\/10\/IMG-SPADE-study.png\" alt=\"\" class=\"wp-image-26805\" srcset=\"https:\/\/www.heartlife.or.jp\/hospital\/wp-content\/uploads\/sites\/2\/2020\/10\/IMG-SPADE-study.png 1020w, https:\/\/www.heartlife.or.jp\/hospital\/wp-content\/uploads\/sites\/2\/2020\/10\/IMG-SPADE-study-300x182.png 300w, https:\/\/www.heartlife.or.jp\/hospital\/wp-content\/uploads\/sites\/2\/2020\/10\/IMG-SPADE-study-768x467.png 768w\" sizes=\"auto, (max-width: 1020px) 100vw, 1020px\" \/><\/figure><\/div>\n\n\n\n<p>\u3000\u6442\u53d6\u7fa4\u306e89%\u3001\u9664\u53bb\u7fa4\u306e83%\u304c\u4e0a\u8a18\u306e\u30ec\u30b8\u30e1\u30f3\u306e\u6307\u793a\u901a\u308a\u306b\u6442\u53d6\u3092\u5b9f\u65bd\u3057\u3066\u304f\u3060\u3055\u3044\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u751f\u5f8c6\u304b\u6708\u6642\u306e\u6bcd\u4e73\u7d99\u7d9a\u7387\u306f\u3001\u6442\u53d6\u7fa472%\u3001\u9664\u53bb\u7fa468%\u3068\u3044\u305a\u308c\u3082\u6c96\u7e04\u770c\u306e\u5e73\u5747\u3068\u540c\u7b49\u306e\u7d99\u7d9a\u7387\u3092\u7dad\u6301\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000\u7814\u7a76\u3092\u9014\u4e2d\u3067\u8131\u9000\u3055\u308c\u305f\u306e\u306f\u3001\u6442\u53d6\u7fa416\u540d\u3001\u9664\u53bb\u7fa414\u540d\u3067\u3001\u305d\u306e\u7406\u7531\u306e\u307b\u3068\u3093\u3069\u304c\u300c\u7d99\u7d9a\u7684\u306a\u53d7\u8a3a\u304c\u56f0\u96e3\u3067\u3042\u3063\u305f\u305f\u3081\u300d\u3067\u3057\u305f\u3002\u4ecb\u5165\u671f\u9593\u4e2d\u3001\u7c89\u30df\u30eb\u30af\u3001\u3082\u3057\u304f\u306f\u5927\u8c46\u7c89\u4e73\u306b\u3088\u308b\u8541\u9ebb\u75b9\u306a\u3069\u306e\u5373\u6642\u578b\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u8a8d\u3081\u305f\u5150\u306f\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000<span data-color=\"#fcb900\" style=\"background: linear-gradient(transparent 60%,rgba(252, 185, 0, 0.7) 0);\" class=\"vk_highlighter\"><span style=\"color:#0693e3\" class=\"tadv-color\">\u672c\u7814\u7a76\u306e\u7d50\u679c\u304b\u3089\u3001\u751f\u5f8c1\u304b\u6708\u304b\u3089\u306e\u5b9a\u671f\u7684\u306a\u7c89\u30df\u30eb\u30af\u306e\u6442\u53d6\u304c\u725b\u4e73\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632\u306b\u6709\u52b9\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u3001\u3055\u3089\u306b\u6bcd\u4e73\u6804\u990a\u306e\u59a8\u3052\u306b\u306a\u3089\u306a\u3044\u3053\u3068\u3082\u8a3c\u660e\u3055\u308c\u307e\u3057\u305f\u3002<\/span><\/span><\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.heartlife.or.jp\/hospital\/wp-content\/uploads\/sites\/2\/2020\/10\/akachan_asemo-e1603697155532.png\" alt=\"\" class=\"wp-image-26957\" width=\"136\" height=\"156\"\/><\/figure><\/div>\n\n\n\n<p>\u3000<span data-color=\"#fcb900\" style=\"background: linear-gradient(transparent 60%,rgba(252, 185, 0, 0.7) 0);\" class=\"vk_highlighter\"><span style=\"color:#cf2e2e\" class=\"tadv-color\">\u4e00\u65b9\u3067\u3001\u6e7f\u75b9\u306f\u7d4c\u76ae\u611f\u4f5c<sup>\u203b1<\/sup>\u306e\u89b3\u70b9\u304b\u3089\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u767a\u75c7\u306e\u5927\u304d\u306a\u30ea\u30b9\u30af\u56e0\u5b50\u3067\u3042\u308b\u305f\u3081\u3001\u6e7f\u75b9\u306e\u7ba1\u7406\u3082\u91cd\u8981\u3060\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u305f\u3060\u5358\u306b\u7c89\u30df\u30eb\u30af\u3092\u6442\u53d6\u3059\u308b\u3088\u3046\u6307\u5c0e\u3059\u308b\u3060\u3051\u3067\u306f\u3001\u6bcd\u4e73\u6804\u990a\u7d99\u7d9a\u3078\u306e\u60aa\u5f71\u97ff\u3082\u61f8\u5ff5\u3055\u308c\u307e\u3059<\/span>\u3002\u3053\u306e\u305f\u3081\u3001\u4ee5\u4e0b\u306e\u70b9\u306b\u7559\u610f\u304c\u5fc5\u8981\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/span><\/p>\n\n\n\n<ul class=\"is-style-vk-check-circle-mark wp-block-list\"><li><strong>\u751f\u5f8c1\u304b\u6708\u304b\u3089\u5c11\u91cf\uff08\u6700\u4f4e10mL\u7a0b\u5ea6\uff09\u3067\u3082\u3044\u3044\u306e\u3067\u7c89\u30df\u30eb\u30af\u3092\u5b9a\u671f\u7684\u306b\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u725b\u4e73\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u4e88\u9632\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b<\/strong><\/li><li><strong>\u6e7f\u75b9\u306e\u6cbb\u7642\u3082\u7a4d\u6975\u7684\u306b\u884c\u3046<\/strong><\/li><li><strong>\u6bcd\u4e73\u6804\u990a\u306e\u7d99\u7d9a\u3082\u63a8\u5968\u3059\u308b<\/strong><\/li><\/ul>\n\n\n\n<p>\u3000\u307e\u305f\u3001<span data-color=\"#fcb900\" style=\"background: linear-gradient(transparent 60%,rgba(252, 185, 0, 0.7) 0);\" class=\"vk_highlighter\">\u672c\u7814\u7a76\u3067\u306f\u7d04500\u540d\u306e\u53c2\u52a0\u8005\u306e\u3046\u30611\u540d\u306f\u751f\u5f8c1\u304b\u6708\u6642\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306e\u30df\u30eb\u30af20mL\u7d4c\u53e3\u8ca0\u8377\u8a66\u9a13\u3067\u8541\u9ebb\u75b9\u3092\u8a8d\u3081\u307e\u3057\u305f\u3002<span style=\"color:#cf2e2e\" class=\"tadv-color\">\u305d\u308c\u307e\u3067\u306b\u5b9a\u671f\u7684\u306a\u30df\u30eb\u30af\u306e\u6442\u53d6\u3092\u884c\u3063\u3066\u304a\u3089\u305a\u3001\u5b89\u5168\u306b\u6442\u53d6\u3067\u304d\u308b\u91cf\u304c\u4e0d\u660e\u306e\u5834\u5408\u306f\u521d\u56de\u306e\u5c0e\u5165\u6642\u306b\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059<\/span>\u3002\u3053\u306e\u5834\u5408\u3001<span style=\"color:#0693e3\" class=\"tadv-color\">\u521d\u56de\u5c0e\u5165\u306f\u533b\u7642\u6a5f\u95a2\u3067\u884c\u3063\u3066\u3044\u305f\u3060\u304f\u304b\u3001\u81ea\u5b85\u3067\u5c0e\u5165\u3059\u308b\u5834\u5408\u306f\u30b9\u30dd\u30a4\u30c8\u3084\u30d9\u30d3\u30fc\u30b9\u30d7\u30fc\u30f3\u306a\u3069\u3092\u4f7f\u7528\u3057\u3066\u6570mL\u304b\u3089\u958b\u59cb\u3057\u3001\u75c7\u72b6\u304c\u306a\u3044\u3053\u3068\u3092\u78ba\u8a8d\u3057\u306a\u304c\u3089\u5897\u91cf\u3059\u308b\u65b9\u6cd5\u304c\u5b89\u5168<\/span>\u304b\u3068\u601d\u308f\u308c\u307e\u3059<\/span>\u3002<\/p>\n\n\n\n<p>\u3000\u307e\u3060\u4e00\u822c\u5316\u3055\u308c\u3066\u3044\u306a\u3044\u65b9\u6cd5\u3067\u3042\u308b\u305f\u3081\u5b9f\u65bd\u306b\u3042\u305f\u3063\u3066\u306f\u6539\u5584\u70b9\u3082\u3042\u308b\u3068\u601d\u308f\u308c\u307e\u3059\u304c\u3001\u4eca\u5f8c\u3001\u5c11\u3057\u3067\u3082\u725b\u4e73\u30a2\u30ec\u30eb\u30ae\u30fc\u3067\u60a9\u3080\u304a\u5b50\u3055\u3093\u304c\u6e1b\u308b\u3053\u3068\u3092\u9858\u3063\u3066\u3001\u3053\u306e\u7814\u7a76\u7d50\u679c\u3092\u304a\u793a\u3057\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000\u672c\u7814\u7a76\u306b\u3054\u53c2\u52a0\u304f\u3060\u3055\u3063\u305f\u7686\u69d8\u3001\u3054\u5bb6\u65cf\u69d8\u306b\u6df1\u8b1d\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"vk_borderBox vk_borderBox-color-green vk_borderBox-background-transparent wp-block-vk-blocks-border-box is-style-vk_borderBox-style-solid-kado-tit-tab\"><div class=\"vk_borderBox_title_container\"><i class=\"\"><\/i><h4 class=\"vk_borderBox_title\">\u203b1\u300c\u7d4c\u76ae\u611f\u4f5c\u300d\u3068\u306f<\/h4><\/div><div class=\"vk_borderBox_body\">\n<p>\u300c\u7d4c\u76ae\u300d\u3068\u306f\u300c\u76ae\u819a\u304b\u3089\u300d\u3001\u300c\u611f\u4f5c\u300d\u3068\u306f\u300c\u30cf\u30a6\u30b9\u30c0\u30b9\u30c8\u3084\u98df\u7269\u306a\u3069\u306b\u5bfe\u3057\u3066\u514d\u75ab\u304c\u50cd\u3044\u3066\u3057\u307e\u3044\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u8d77\u3053\u3059\u4f53\u8cea\u306b\u306a\u3063\u3066\u3057\u307e\u3046\u3053\u3068\u300d\u3092\u8a00\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6b63\u5e38\u306a\u76ae\u819a\u306f\u89d2\u8cea\u306b\u5b88\u3089\u308c\u3066\u3044\u3066\u3001\u7570\u7269\u304c\u4fb5\u5165\u3057\u306b\u304f\u3044\u4f5c\u308a\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u4e7e\u71e5\u3084\u6e7f\u75b9\u30fb\u63bb\u304d\u50b7\u306a\u3069\u3067\u89d2\u8cea\u304c\u58ca\u3055\u308c\u3001\u30a2\u30ec\u30eb\u30b2\u30f3\u304c\u76ae\u819a\u306e\u30d0\u30ea\u30a2\u3092\u901a\u904e\u3057\u3066\u8868\u76ae\u3084\u771f\u76ae\u306b\u4fb5\u5165\u3059\u308b\u3068\u3001\u514d\u75ab\u7d30\u80de\u3068\u53cd\u5fdc\u3057\u3066\u611f\u4f5c\u304c\u8d77\u3053\u308a\u307e\u3059\u3002 \u3053\u308c\u3092\u300c\u7d4c\u76ae\u611f\u4f5c\u300d\u3068\u3044\u3044\u307e\u3059\u3002<\/p>\n<\/div><\/div>\n\n\n\n<p><\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u53c2\u8003\u6587\u732e<\/p><cite>1. Prescott SL, et al. A global survey of changing patterns of food allergy burden in children. World Allergy Organ J 2013<br>2. George Du Toit, et.al. Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy \u201cLearning Early About Peanut Allergy (LEAP) trial. N Engl J Med. 2015<br>3. Osamu Natsume, et al. Two-step egg introduction for prevention of egg allergy in high-risk infants with eczema (PETIT): a randomized, double-blind, placebo-controlled trial. The Lancet 2016<br>4. Katz Y, et al. Early exposure to cow\u2019s milk protein is protective against IgE-mediated cow\u2019s milk protein allergy. J Allergy Clin Immunol. 2010<br>5. Peters RL, et al. Early exposure to cow\u2019s milk protein is associated with a reduced risk of cow\u2019s milk allergic outcomes. J Allergy Clin Immunol Pract. 2019<br>6. Tezuka J, et al. Possible association between early formula and reduced risk of cow\u2019s milk allergy: the Japan Environment and Children\u2019s Study. Clinical &amp; Experimental Allergy. 2020<br>7. Lowe AJ, et al. Effect of a partially hydrolyzed whey infant formula at weaning on risk of allergic disease in high-risk children: a randomized controlled trial. J Allergy Clin Immunol. 2011<br>8. Perkin MR, et al. Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants. N Engl J Med. 2016<br>9. Urashima M, et al. Primary Prevention of Cow&#8217;s Milk Sensitization and Food Allergy by Avoiding Supplementation with Cow&#8217;s Milk Formula at Birth: A Randomized Clinical Trial. JAMA Pediatr. 2019<\/cite><\/blockquote>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3000\u904e\u53bb20\u5e74\u9593\u306b\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u60a3\u8005\u6570\u306f\u5897\u52a0\u3057\u3066\u304a\u308a\u3001\u7279\u306b\u5148\u9032\u56fd\u3067\u306f\u5c0f\u5150\u306e\u7d0410%\u306b\u9054\u3059\u308b\u3068\u3044\u3046\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u30021 \u3000\u7c73\u56fd\u5c0f\u5150\u79d1\u5b66\u4f1a\uff08American Academy of Pediatrics\uff0c\u901a\u79f0AAP\uff09\u306f\u30012000 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":225,"menu_order":63,"comment_status":"closed","ping_status":"closed","template":"page-dept.php","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[50],"class_list":["post-26788","page","type-page","status-publish","hentry","category-clinical-dept"],"_links":{"self":[{"href":"https:\/\/www.heartlife.or.jp\/hospital\/wp-json\/wp\/v2\/pages\/26788","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.heartlife.or.jp\/hospital\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.heartlife.or.jp\/hospital\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.heartlife.or.jp\/hospital\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.heartlife.or.jp\/hospital\/wp-json\/wp\/v2\/comments?post=26788"}],"version-history":[{"count":43,"href":"https:\/\/www.heartlife.or.jp\/hospital\/wp-json\/wp\/v2\/pages\/26788\/revisions"}],"predecessor-version":[{"id":27239,"href":"https:\/\/www.heartlife.or.jp\/hospital\/wp-json\/wp\/v2\/pages\/26788\/revisions\/27239"}],"up":[{"embeddable":true,"href":"https:\/\/www.heartlife.or.jp\/hospital\/wp-json\/wp\/v2\/pages\/225"}],"wp:attachment":[{"href":"https:\/\/www.heartlife.or.jp\/hospital\/wp-json\/wp\/v2\/media?parent=26788"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.heartlife.or.jp\/hospital\/wp-json\/wp\/v2\/categories?post=26788"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}